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Hiromi Iwasaki Selected Research

proto-oncogene protein Spi-1

1/2006Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
4/2005Potential autoregulation of transcription factor PU.1 by an upstream regulatory element.
6/2004Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

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Hiromi Iwasaki Research Topics

Disease

12Multiple Myeloma
07/2022 - 06/2010
11Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2022 - 06/2004
11Graft vs Host Disease (Graft-Versus-Host Disease)
11/2019 - 01/2010
9Leukemia
01/2017 - 10/2002
7Lymphoma (Lymphomas)
12/2022 - 03/2012
7Neoplasms (Cancer)
12/2022 - 01/2006
7Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
01/2022 - 01/2010
5Hematologic Neoplasms (Hematological Malignancy)
06/2022 - 06/2010
4Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
12/2022 - 07/2020
4Disease Progression
01/2022 - 01/2016
3T-Cell Lymphoma (Lymphoma, T Cell)
01/2021 - 01/2010
3Bronchiolitis Obliterans Syndrome
01/2021 - 01/2009
3Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
01/2021 - 10/2019
3Acute Promyelocytic Leukemia
09/2020 - 12/2010
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
07/2020 - 11/2003
2Lymphoproliferative Disorders (Lymphoproliferative Disorder)
08/2022 - 01/2021
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
04/2022 - 01/2009
2Lymphopenia (Lymphocytopenia)
01/2022 - 11/2015
2Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
03/2020 - 04/2018
2Hemorrhage
03/2020 - 04/2018
2Pain (Aches)
12/2018 - 11/2010
2Myelitis
12/2018 - 11/2010
2Encephalitis (Encephalitis, Rasmussen)
12/2018 - 11/2010
2Primary Myelofibrosis (Myelosclerosis)
09/2017 - 01/2016
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2017 - 03/2015
2Essential Thrombocythemia
01/2017 - 01/2016
2Philadelphia Chromosome
01/2017 - 03/2015
2Anemia
11/2015 - 01/2007
2Neutropenia
11/2015 - 08/2014
2Pneumonia (Pneumonitis)
11/2015 - 10/2008
2Infections
01/2015 - 01/2011
2Hypoxia (Hypoxemia)
03/2013 - 10/2008
2Hemorrhagic Cystitis
08/2012 - 03/2012
2Aspergillosis
07/2011 - 06/2010
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2022
1Hematologic Diseases (Blood Diseases)
10/2021
1Rheumatoid Arthritis
01/2021
1Waldenstrom Macroglobulinemia (Macroglobulinemia)
07/2020

Drug/Important Bio-Agent (IBA)

9Dexamethasone (Maxidex)FDA LinkGeneric
07/2022 - 08/2014
5Proteins (Proteins, Gene)FDA Link
12/2022 - 12/2004
5Rituximab (Mabthera)FDA Link
12/2022 - 08/2012
5Lenalidomide (CC 5013)FDA Link
07/2022 - 04/2017
5Bortezomib (Velcade)FDA Link
05/2020 - 01/2013
5DNA (Deoxyribonucleic Acid)IBA
01/2020 - 12/2004
5Transcription Factors (Transcription Factor)IBA
08/2017 - 06/2004
4Methotrexate (Mexate)FDA LinkGeneric
08/2022 - 01/2019
4mogamulizumabIBA
01/2021 - 03/2013
4Tyrosine Kinase InhibitorsIBA
07/2020 - 03/2015
4Adrenal Cortex Hormones (Corticosteroids)IBA
11/2018 - 10/2008
3LigandsIBA
08/2022 - 06/2021
3pomalidomideIBA
07/2022 - 01/2015
3Calcineurin InhibitorsIBA
11/2019 - 11/2010
3Dasatinib (BMS 354825)FDA Link
01/2017 - 03/2015
3Aprepitant (Emend)FDA Link
09/2013 - 01/2013
3Melphalan (Alkeran)FDA LinkGeneric
09/2013 - 01/2013
3proto-oncogene protein Spi-1IBA
01/2006 - 06/2004
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2022 - 01/2022
2Vincristine (Oncovin)FDA LinkGeneric
12/2022 - 01/2022
2Doxorubicin (Adriamycin)FDA LinkGeneric
12/2022 - 01/2022
2Prednisolone (Predate)FDA LinkGeneric
01/2022 - 03/2020
2Bendamustine HydrochlorideFDA Link
01/2022 - 07/2017
2Indicators and Reagents (Reagents)IBA
12/2020 - 01/2011
2Tretinoin (Retinoic Acid)FDA LinkGeneric
09/2020 - 09/2020
2GemcitabineFDA Link
07/2020 - 10/2019
2Proteasome InhibitorsIBA
05/2020 - 04/2017
2Immunomodulating AgentsIBA
05/2020 - 04/2017
2Inosine Triphosphate (ITP)IBA
03/2020 - 04/2018
2Mycophenolic Acid (Cellcept)FDA LinkGeneric
11/2019 - 01/2017
2MethylprednisoloneFDA LinkGeneric
11/2018 - 10/2008
2Thalidomide (Thalomid)FDA Link
04/2017 - 08/2014
2Janus Kinase 2IBA
01/2017 - 01/2016
2nilotinibFDA Link
01/2017 - 01/2017
2Monoclonal AntibodiesIBA
01/2016 - 03/2013
2Mucin-3IBA
09/2015 - 12/2010
2DefensinsIBA
10/2013 - 07/2012
2AntiemeticsIBA
02/2013 - 01/2013
1carboxyl radical (COO-)IBA
12/2022
1Prednisone (Sone)FDA LinkGeneric
12/2022
1daratumumabIBA
07/2022
1Mitoxantrone (Novantrone)FDA LinkGeneric
06/2022
1Cytarabine (Cytosar-U)FDA LinkGeneric
06/2022
1Daunorubicin (Cerubidine)FDA LinkGeneric
06/2022
1alvocidib (flavopiridol)IBA
06/2022
1EmulsionsIBA
04/2022
1Azacitidine (5 Azacytidine)FDA Link
12/2021
1Antirheumatic Agents (DMARD)IBA
01/2021
1Biological ProductsIBA
01/2021
1pembrolizumabIBA
11/2020
1Complement System Proteins (Complement)IBA
07/2020
1romidepsin (FK228)FDA Link
10/2019
1Cisplatin (Platino)FDA LinkGeneric
10/2019
1Factor VIII (Coagulation Factor VIII)IBA
06/2019

Therapy/Procedure

13Therapeutics
07/2022 - 01/2005
13Hematopoietic Stem Cell Transplantation
01/2021 - 01/2010
12Drug Therapy (Chemotherapy)
01/2022 - 10/2009
12Stem Cell Transplantation
12/2021 - 07/2011
10Transplantation
10/2021 - 10/2009
3Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
01/2021 - 01/2013
3Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2021 - 10/2008
1Cell Transplantation
07/2020